*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : MA2275100 CHEMICAL NAME : Glutamine, L- CAS REGISTRY NUMBER : 56-85-9 BEILSTEIN REFERENCE NO. : 1723797 REFERENCE : 4-04-00-03038 (Beilstein Handbook Reference) LAST UPDATED : 199706 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C5-H10-N2-O3 MOLECULAR WEIGHT : 146.17 WISWESSER LINE NOTATION : ZV2YZVQ COMPOUND DESCRIPTOR : Drug Mutagen Human SYNONYMS/TRADE NAMES : * 2-Aminoglutaramic acid * L-2-Aminoglutaramidic acid * Cebrogen * Glumin * Glutamic acid amide * Glutamic acid 5-amide * Glutamine * gamma-Glutamine * L-Glutamine * Levoglutamid * Levoglutamide * Stimulina *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 27 mg/kg/1W-I TOXIC EFFECTS : Behavioral - euphoria REFERENCE : AJPSAO American Journal of Psychiatry. (American Psychiatric Assoc., Circulation Dept., 1400 K St., NW, Washington, DC 20005) V.78- 1921- Volume(issue)/page/year: 141,1302,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,228,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 21700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,228,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 260 mg/kg/30D-I TOXIC EFFECTS : Behavioral - food intake (animal) Blood - changes in spleen Related to Chronic Data - death REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 8,902,1974 ** MUTATION DATA ** TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 10 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4814 No. of Facilities: 841 (estimated) No. of Industries: 4 No. of Occupations: 14 No. of Employees: 8491 (estimated) No. of Female Employees: 5700 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***