*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MB9127000
CHEMICAL NAME           : Glycine, N-carbamoyl-N-nitroso-, ethyl ester
CAS REGISTRY NUMBER     : 67792-85-2
BEILSTEIN REFERENCE NO. : 1787039
REFERENCE               : 0-04-00-00380 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H9-N3-O4
MOLECULAR WEIGHT        : 175.17
WISWESSER LINE NOTATION : ZVNNO&1VO2
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Carbamoyl-N-nitrosoglycine ethyl ester
   * N-Ethoxycarbonylmethyl-N-nitrosourea
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 12,601,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 80 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 202,193,1988
 
                            *** END OF RECORD ***