*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7676300
CHEMICAL NAME           : Acridine, 9-(o-chloroanilino)-, hydrochloride
CAS REGISTRY NUMBER     : 14408-86-7
LAST UPDATED            : 199312
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H13-Cl-N2.Cl-H
MOLECULAR WEIGHT        : 341.25
WISWESSER LINE NOTATION : T C666 BNJ IMR BG &GH
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 9-Acridinamine, N-(2-chlorophenyl)-, hydrochloride
   * 9-(o-Chloroanilino)acridine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD10 - Lethal Dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,170,1981
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 41 umol/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,170,1981
 
                            *** END OF RECORD ***