*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AR7690000 CHEMICAL NAME : Acridine, 6-chloro-9-((3-((2-chloroethyl)thio)propyl)amino)-2-m ethoxy-, hydrochloride CAS REGISTRY NUMBER : 99711-15-6 LAST UPDATED : 199109 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C19-H20-Cl2-N2-O-S.xCl-H MOLECULAR WEIGHT : 650.59 WISWESSER LINE NOTATION : T C666 BNJ EG IM3S2G LO1 &GH COMPOUND DESCRIPTOR : Tumorigen SYNONYMS/TRADE NAMES : * 6-Chloro-9-(3-(2-chloroethyl)mercaptopropylamino)-2-methoxyacridine hydrochloride * ICR 342 * 2-Methoxy-6-chloro-9-(3-(2-chloroethyl)mercaptopropylamino)acridine hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 12 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2423,1976 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6500 ug/kg TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2423,1976 *** END OF RECORD ***