*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR9534000
CHEMICAL NAME           : Acridine, 1,2,3,4-tetrahydro-9-butylamino-
CAS REGISTRY NUMBER     : 316-15-4
BEILSTEIN REFERENCE NO. : 0481616
REFERENCE               : 5-22-10-00480 (Beilstein Handbook Reference)
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H22-N2
MOLECULAR WEIGHT        : 254.41
WISWESSER LINE NOTATION : T C666 BNT&&J IM4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 9-Acridinamine, 1,2,3,4-tetrahydro-N-butyl-
   * Acridine, 9-butylamino-1,2,3,4-tetrahydro-
   * Bucricaine
   * 9-Butylamino-1,2,3,4-tetrahydroacridine
   * 4-Butylamino-2,3-tetramethylenequinoline
   * 1,2,3,4-Tetrahydro-N-butyl-9-acridinamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,483,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - analgesia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 5,654,1971
 
                            *** END OF RECORD ***