*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AR9534000 CHEMICAL NAME : Acridine, 1,2,3,4-tetrahydro-9-butylamino- CAS REGISTRY NUMBER : 316-15-4 BEILSTEIN REFERENCE NO. : 0481616 REFERENCE : 5-22-10-00480 (Beilstein Handbook Reference) LAST UPDATED : 199803 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H22-N2 MOLECULAR WEIGHT : 254.41 WISWESSER LINE NOTATION : T C666 BNT&&J IM4 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 9-Acridinamine, 1,2,3,4-tetrahydro-N-butyl- * Acridine, 9-butylamino-1,2,3,4-tetrahydro- * Bucricaine * 9-Butylamino-1,2,3,4-tetrahydroacridine * 4-Butylamino-2,3-tetramethylenequinoline * 1,2,3,4-Tetrahydro-N-butyl-9-acridinamine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,483,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 5,654,1971 *** END OF RECORD ***