*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AT7785000
CHEMICAL NAME           : Acryloyl chloride, trichloro-
CAS REGISTRY NUMBER     : 815-58-7
BEILSTEIN REFERENCE NO. : 1754789
REFERENCE               : 4-02-00-01486 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C3-Cl4-O
MOLECULAR WEIGHT        : 193.83
WISWESSER LINE NOTATION : GYGUYGVG
COMPOUND DESCRIPTOR     : Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Chlorid kyseliny trichlorakrylove
   * 2-Propenoyl chloride, 2,3,4-trichloro-
   * TCAT
   * Trichloroacryloyl chloride
   * 2,3,3-Trichloroacryloyl chloride
   * Trichloracrylyl chloride
   * Trichloroacrylyl chloride
   * 2,3,4-Trichloro-2-propenoyl chloride
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 270 ug
REACTION SEVERITY       : Mild
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2560 ug/5S
REACTION SEVERITY       : Mild
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 107 ppm/30M
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 ppm/30M
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 67 ppm/30M
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   XEURAQ U.S. Atomic Energy Commission, University of Rochester, Research and
   Development Reports. (Rochester, NY)  Volume(issue)/page/year: MDDC-1715
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 117,21,1983

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***