*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7270000
CHEMICAL NAME           : Acridine, 4-amino-
CAS REGISTRY NUMBER     : 578-07-4
BEILSTEIN REFERENCE NO. : 0142257
REFERENCE               : 5-22-11-00008 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C13-H10-N2
MOLECULAR WEIGHT        : 194.25
WISWESSER LINE NOTATION : T C666 BNJ DZ
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 4-Acridinamine
   * 1-Aminoacridine
   * 4-Aminoacridine
   * 5-Aminoacridine
   * 4-Aminoakridin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 910 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJEPA5 British Journal of Experimental Pathology.  (Blackwell Scientific
   Pub. Ltd., POB 88, Oxford, UK)  V.1-    1920-  Volume(issue)/page/year:
   28,1,1947
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2500 ug/L
REFERENCE :
   NNBYA7 Nature (London), New Biology.  (Basingstoke, Hants., UK)  V.229-246,
   1971-73.  For publisher information, see NATUAS.  Volume(issue)/page/year:
   236,19,1972
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 72 mg/L
REFERENCE :
   JMOBAK Journal of Molecular Biology.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year: 3,762,1961
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 2 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 4,289,1967

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: S cerevisiae-forward mutation; S
   cerevisiae-reversion

 
                            *** END OF RECORD ***