*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU1627000
CHEMICAL NAME           : Actinomycin D, 7-((tricyclo(3.3.1.1(sup
                          3,7))dec-1-ylcarbonyl)oxy)-, dihydrate
CAS REGISTRY NUMBER     : 78566-17-3
LAST UPDATED            : 198508
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C73-H100-N12-O18.2H2-O
MOLECULAR WEIGHT        : 1469.89
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 7-(1'-Adamantoyloxy)actinomycin D dihydrate
   * 7-((Tricyclo(3.3.1.1(sup 3,7))dec-1-ylcarbonyl)oxy)actinomycin D  
   dihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 730 nmol/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,1052,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 176 nmol/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,1052,1981
 
                            *** END OF RECORD ***