*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU1830000
CHEMICAL NAME           : Actinomycin L
CAS REGISTRY NUMBER     : 102488-99-3
LAST UPDATED            : 199510
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * Actinomycin 2104 L
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4725 ug/kg/35W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BKNJA5 Biken Journal.  (Research Institute for Microbial Diseases, Osaka
   Univ., 3-1 Yamadaoka, Suita, Osaka-fu, Japan)  V.1-    1958-
   Volume(issue)/page/year: 2,105,1959

                              *** REVIEWS ***
 
   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 10,29,1976

   IARC Cancer Review:Human No Adequate Data
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 10,29,1976

 
                            *** END OF RECORD ***