*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU6256000
CHEMICAL NAME           : Adenine,
                          9-(6-deoxy-beta-D-erythro-hex-5-enulofuranosyl)-
CAS REGISTRY NUMBER     : 2004-04-8
OTHER CAS REGISTRY NOS. : 1373-27-9
LAST UPDATED            : 199106
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H13-N5-O4
MOLECULAR WEIGHT        : 279.29
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * A 14
   * Adenine,  
   9-(tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)-
   * Angustmycin A
   * Antibiotic A 14
   * Decoyinin
   * Decoyinine
   * 9-(6-Deoxy-beta-D-erythro-hex-5-enulofuranosyl)adenine
   * 9H-Purin-6-amine, 9-(6-deoxy-beta-D-erythro-hex-5-en-2-ulofuranosyl)-
   * 9-(Tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)adenine
   * U-7984
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
   Antibiotics, A Program of Upjohn Company Research Laboratory."  (Kalamazoo,
   MI 49001)  Volume(issue)/page/year: 2(6),-,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
   Antibiotics, A Program of Upjohn Company Research Laboratory."  (Kalamazoo,
   MI 49001)  Volume(issue)/page/year: 2(6),-,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,294,1981
 
                            *** END OF RECORD ***