*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU7333800
CHEMICAL NAME           : Adenosine,
                          5'-((3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy
                          -, hydroxide, inner salt, (S)-,
                          4-methylbenzenesulfonate sulfate (1:2:2) (salt)
CAS REGISTRY NUMBER     : 58994-55-1
LAST UPDATED            : 199209
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C15-H22-N6-O5-S.2C7-H8-O3-S.2H2-O4-S
MOLECULAR WEIGHT        : 907.01
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * S-Adenosylmethionine disulfate ditosylate
   * Gumbaral
   * Samyr
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 66,1541,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 66,1541,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 66,1541,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 560 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 66,1541,1975
 
                            *** END OF RECORD ***