*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : MD0907600
CHEMICAL NAME : Glycols, polyethylene,
mono((1,1,3,3-tetramethylbutyl)phenyl) ether
CAS REGISTRY NUMBER : 9036-19-5
LAST UPDATED : 199710
DATA ITEMS CITED : 15
MOLECULAR FORMULA : (C2-H4-O)n-C14-H22-O
WISWESSER LINE NOTATION : /*O2*/ **1X1&1&1X1&1&R X *Q
COMPOUND DESCRIPTOR : Mutagen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Charger E
* Ethoxylated octyl phenol
* Ethylan CP
* Igepal CA
* Igepal CA 520
* Neutronyx 622
* Neutronyx 675
* Nonidet P40
* Nonion HS 206
* Nonion HS 208
* NP-40
* Octylphenoxypoly(ethoxyethanol)
* tert-Octylphenoxypoly(ethoxyethanol)
* Octylphenoxypoly(ethyleneoxy)ethanol
* tert-Octylphenoxy poly(oxyethylene)ethanol
* OP 1062
* Polyethylene glycol mono(octylphenyl) ether
* Polyethylene glycol octylphenyl ether
* Poly(ethylene oxide)octylphenyl ether
* Poly(oxy-1,2-ethanediyl),
alpha-((1,1,3,3-tetramethylbutyl)phenyl)-omega-hydroxy-
* Polyoxyethylene monooctylphenyl ether
* Poly(oxyethylene)octylphenol ether
* Poly(oxyethylene)octylphenyl ether
* Secopal OP 20
* Synperonic OP
* Synperonic OP 10
* T45
* T 45 (Polyglycol)
* Triton X 15
* Triton X 114
* Triton X 207
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1%
REACTION SEVERITY : Severe
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,665,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 770 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,665,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 70 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 8750 mg/kg/30D-I
TOXIC EFFECTS :
Related to Chronic Data - death
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 38,428,1949
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 5 ppm
REFERENCE :
ENPBBC Environmental Physiology and Biochemistry. (Copenhagen, Denmark)
V.2-5, 1972-75. Discontinued. Volume(issue)/page/year: 5,84,1975
TYPE OF TEST : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE : Intraperitoneal
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 870 mg/kg
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,665,1984
TYPE OF TEST : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 10200 mg/kg
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
22,665,1984
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION : 10 ppm
REFERENCE :
ENPBBC Environmental Physiology and Biochemistry. (Copenhagen, Denmark)
V.2-5, 1972-75. Discontinued. Volume(issue)/page/year: 5,84,1975
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 81435
No. of Facilities: 42544 (estimated)
No. of Industries: 250
No. of Occupations: 129
No. of Employees: 388256 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X5849
No. of Facilities: 35278 (estimated)
No. of Industries: 227
No. of Occupations: 160
No. of Employees: 687698 (estimated)
No. of Female Employees: 226942 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***