*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MD0907700
CHEMICAL NAME           : Glycols, polyethylene,
                          mono(p-(1,1,3,3-tetramethylbutyl)phenyl) ether
CAS REGISTRY NUMBER     : 9002-93-1
OTHER CAS REGISTRY NOS. : 9010-43-9
LAST UPDATED            : 199803
DATA ITEMS CITED        : 14
MOLECULAR FORMULA       : (C2-H4-O)n.C14-H22-O
WISWESSER LINE NOTATION : /*O2*/ **1X1&1&1X1&1&R D *Q
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Antarox A-200
   * Hydrol SW
   * Polyethylene glycol mono(p-(1,1,3,3-tetramethylbutyl)phenyl) ether
   * Polyethylene glycol p-1,1,3,3-tetramethylbutylphenyl ether
   * Poly(oxy-1,2-ethanediyl),  
   alpha-(4-(1,1,3,3-tetramethylbutyl)phenyl)-omega-hydroxy-
   * Preceptin
   * Texofor FP 300
   * Triton X
   * Triton X 100
   * Triton X 101
   * Triton X 165
   * Triton X 305
   * Triton X 405
   * Triton X 705
   * TX 100
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg
REACTION SEVERITY       : Moderate
REFERENCE :
   PSTGAW Proceedings of the Scientific Section of the Toilet Goods
   Association. (Washington, DC) No.1-48, 1944-67.  Discontinued.
   Volume(issue)/page/year: 20,16,1953
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSTGAW Proceedings of the Scientific Section of the Toilet Goods
   Association. (Washington, DC) No.1-48, 1944-67.  Discontinued.
   Volume(issue)/page/year: 20,16,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   101,173,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 154 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BEBMAE Byulleten' Eksperimental'noi Biologii i Meditsiny.  Bulletin of
   Experimental Biology and Medicine.  For English translation, see BEXBAN.
   (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 112(10),423,1991
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 65500 mg/kg
SEX/DURATION            : female 26 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 22,668,1970
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 22,668,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 21 mg/L
REFERENCE :
   WATRAG Water Research.  (Pergamon Press Ltd., Headington Hill Hall, Oxford
   OX3 0BW, UK) V.1-    1967-  Volume(issue)/page/year: 19,677,1985
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 14 mg/L
REFERENCE :
   WATRAG Water Research.  (Pergamon Press Ltd., Headington Hill Hall, Oxford
   OX3 0BW, UK) V.1-    1967-  Volume(issue)/page/year: 19,677,1985
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 200 ppm
REFERENCE :
   AMOKAG Acta Medicia Okayama.  (Okayama Univ. Medical School, Okayama, Japan)
    V.27    1973-  Volume(issue)/page/year: 32,1,1978

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - A1896
       No. of Facilities: 4670 (estimated)
       No. of Industries: 33
       No. of Occupations: 52
       No. of Employees: 24863 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X7316
       No. of Facilities: 15151 (estimated)
       No. of Industries: 95
       No. of Occupations: 103
       No. of Employees: 232961 (estimated)
       No. of Female Employees: 97685 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***