*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MD8470000
CHEMICAL NAME           : Gramicidin S
CAS REGISTRY NUMBER     : 113-73-5
BEILSTEIN REFERENCE NO. : 0605227
LAST UPDATED            : 199709
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C60-H92-N12-O10
MOLECULAR WEIGHT        : 1141.64
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Gramicidin C
   * Gramicin S 1
   * Gramicin S-A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARSMA9 American Review of Soviet Medicine.  (New York, NY)  V.1-5, 1943-48.
   Discontinued.  Volume(issue)/page/year: 2,134,1944
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),271,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 3,1529,1978
 
                            *** END OF RECORD ***