*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : ME1200000 CHEMICAL NAME : Grayanotoxan-6-one, 10,20-didehydro-3,5,14,16-tetrahydroxy-, (3-beta,14R)- CAS REGISTRY NUMBER : 28371-51-9 BEILSTEIN REFERENCE NO. : 2674036 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H30-O5 MOLECULAR WEIGHT : 350.50 COMPOUND DESCRIPTOR : Natural Product SYNONYMS/TRADE NAMES : * 6-Dehydrograyanotoxin II * (3-beta,14R)-10,20-Didehydro-3,5,14,16-tetrahydroxygrayanotoxan-6-one *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >100 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - ataxia Behavioral - muscle contraction or spasticity REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 35,303,1976 *** END OF RECORD ***