*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : ME1220000 CHEMICAL NAME : Grayanotoxan-6-one, 3,5,10,14,16-pentahydroxy-, (3-beta,14R)- CAS REGISTRY NUMBER : 54781-74-7 LAST UPDATED : 199406 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H32-O6 MOLECULAR WEIGHT : 368.52 COMPOUND DESCRIPTOR : Natural Product SYNONYMS/TRADE NAMES : * 6-Dehydrograyanotoxin III * 6-Ketograyanotoxin III * (3-beta,14R)-3,5,10,14,16-Pentahydroxygrayanotoxan-6-one *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >100 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - ataxia Behavioral - muscle contraction or spasticity REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 35,303,1976 *** END OF RECORD ***