*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ME1290000
CHEMICAL NAME           : Grayanotox-10(20)-ene-3,5,6,14,16-pentol, cyclic
                          3,5:14,16-bis(ethylidene acetal), (3-beta,6-
                          beta,14R)-
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H36-O5
MOLECULAR WEIGHT        : 404.60
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * 3,5:14,16-Diethylidene-grayanotoxin II
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   35,303,1976
 
                            *** END OF RECORD ***