*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : ME8575000 CHEMICAL NAME : Guanidine, 1-benzyl-2,3-dimethyl-, sulfate(2:1) CAS REGISTRY NUMBER : 114-85-2 LAST UPDATED : 199203 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C20-H30-N6.H2-O4-S MOLECULAR WEIGHT : 452.64 WISWESSER LINE NOTATION : 1NUYM1&M1R 2 &WSQQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Batel * Bendogen * Bentanidol * Benzaidin * Benzanidin * Benzanidine * Benzoxine * 1-Benzyl-2,3-dimethyl-guanidine sulfate (1:1/2) * N-Benzyl-N',N''-dimethylguanidine sulphate * Betaling * Betanidol * Betanidole * Bethanid * Bethanidine, hemisulfate * Bethanidine sulfate * BW 467 C-60 * 467-C-60 * N,N-Dimethyl''-(phenylmethyl)guanidine sulphate (2:1) * Esbatal * Estabal * Eusmanid * Guanidine, N,N'-dimethyl-N"-(phenylmethyl)-, sulfate (2:1) * Hypersin * NSC-106563 * Regulin * Tenathan *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 72,837,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 520 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 20,36,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 20,36,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 260 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 20,36,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 12 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 20,36,1963 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 20,36,1963 *** END OF RECORD ***