*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ME8945000
CHEMICAL NAME           : Guanidine, 1-tert-butyl-2-cyano-3-(3-pyridyl)-
CAS REGISTRY NUMBER     : 60559-94-6
BEILSTEIN REFERENCE NO. : 0479173
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H15-N5
MOLECULAR WEIGHT        : 217.31
WISWESSER LINE NOTATION : T6NJ CMYUNCN&MX1&1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-tert-Butyl-2-cyano-3-(3-pyridyl)guanidine
   * Guanidine, N-cyano-N'-(1,1-dimethylethyl)-N''-3-pyridinyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 278 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,773,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,773,1978
 
                            *** END OF RECORD ***