*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF3100000
CHEMICAL NAME           : Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 76487-49-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H22-N4.Cl-H
MOLECULAR WEIGHT        : 234.82
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Guanethidine hydrochloride
   * (2-(Hexahydro-1(2H)-azocinyl)ethyl)guanidine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 238 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 19,867,1981
 
                            *** END OF RECORD ***