*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF3570000
CHEMICAL NAME           : Guanidine, (2-hydroxyethyl)-, benzoate (ester),
                          mononitrate
CAS REGISTRY NUMBER     : 19623-18-8
LAST UPDATED            : 198612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H13-N3-O2.H-N-O3
MOLECULAR WEIGHT        : 270.28
WISWESSER LINE NOTATION : MUYZM2OVR &..H..N-O3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Benzoyloxy-ethylguanidine nitrate
   * HM-198
   * (2-Hydroxyethyl)guanidine benzoate (ester), mononitrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 175,193,1968
 
                            *** END OF RECORD ***