*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF6477000
CHEMICAL NAME           : Guanidine,
                          (2-(tetrahydro-1,4-oxazepin-4(5H)-yl)ethyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 98748-91-5
LAST UPDATED            : 198806
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H18-N4-O.2Cl-H
MOLECULAR WEIGHT        : 259.22
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(2-Guanidinoethyl)-perhydro-1,4-oxazepine dihydrochloride
   * (2-(Tetrahydro-1,4-oxazepin-4(5H)-yl)ethyl)guanidine dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 42,55,1985
 
                            *** END OF RECORD ***