*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MG0185000
CHEMICAL NAME           : Guar gum
CAS REGISTRY NUMBER     : 9000-30-0
OTHER CAS REGISTRY NOS. : 57406-68-5
                          57406-71-0
LAST UPDATED            : 199710
DATA ITEMS CITED        : 13
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 1212A
   * A-20D
   * Burtonite V-7-E
   * Cyamopsis gum
   * Dealca TP1
   * Dealca TP2
   * Decorpa
   * Galactasol
   * Gendriv 162
   * Guar
   * Guaran
   * Guar flour
   * Gum cyamopsis
   * Gum guar
   * Indalca AG
   * Indalca AG-BV
   * Indalca AG-HV
   * Jaguar
   * Jaguar 6000
   * Jaguar A 20 B
   * Jaguar A 20D
   * Jaguar A 40F
   * Jaguar gum A-20-D
   * Jaguar No.124
   * Jaguar plus
   * J 2Fp
   * Lycoid DR
   * NCI-C50395
   * Regonol
   * Rein guarin
   * Supercol G.F.
   * Supercol U powder
   * Syngum D 46D
   * Uni-Guar
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6770 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 19,287,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FDRLI* Food & Drug Research Laboratories, Inc., Papers.  (P.O. Box 107, Rt.
   17C, Waverly, NY 14892-0107)  Volume(issue)/page/year: 124,-,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 7 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FDRLI* Food & Drug Research Laboratories, Inc., Papers.  (P.O. Box 107, Rt.
   17C, Waverly, NY 14892-0107)  Volume(issue)/page/year: 124,-,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 6 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FDRLI* Food & Drug Research Laboratories, Inc., Papers.  (P.O. Box 107, Rt.
   17C, Waverly, NY 14892-0107)  Volume(issue)/page/year: 124,-,1976
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 228 gm/kg/13W-C
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-229,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 451 gm/kg/91D-C
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in bladder weight
   Endocrine - hypoglycemia
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 19,287,1981
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1092 gm/kg/13W-C
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-229,1982

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83111
       No. of Facilities: 208 (estimated)
       No. of Industries: 10
       No. of Occupations: 20
       No. of Employees: 3024 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83111
       No. of Facilities: 2264 (estimated)
       No. of Industries: 20
       No. of Occupations: 41
       No. of Employees: 44736 (estimated)
       No. of Female Employees: 6883 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: D melanogaster Sex-linked lethal
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NTP Carcinogenesis Bioassay (feed);no evidence:mouse,rat
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-229,82

 
                            *** END OF RECORD ***