*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : MH5425000
CHEMICAL NAME : HEF-2 jet fuel
SUBSTANCE DEFINITION :
Mixture of alkylpentaborane derivatives
REFERENCE :
CRDLR* U.S. Army Chemical Research & Development Laboratory, Technical
Report. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 3035,1960
LAST UPDATED : 199512
DATA ITEMS CITED : 18
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New
York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 12 ppm/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
CRDLR* U.S. Army Chemical Research & Development Laboratory, Technical
Report. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 3035,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 63 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 89 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 11 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New
York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 10 ppm/4H
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
CRDLR* U.S. Army Chemical Research & Development Laboratory, Technical
Report. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 3035,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 32 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 7 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New
York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 316 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 79 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
XAWPA2 U.S. Army Chemical Warfare Laboratories. (Army Chemical Center, MD)
Volume(issue)/page/year: CWL 2-10,1958
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1900 ppb/6H/30D-I
TOXIC EFFECTS :
Behavioral - irritability
Blood - normocytic anemia
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
CRDLR* U.S. Army Chemical Research & Development Laboratory, Technical
Report. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 3035,1960
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 1900 ppb/6H/22D-I
TOXIC EFFECTS :
Behavioral - irritability
Blood - changes in other cell count (unspecified)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
CRDLR* U.S. Army Chemical Research & Development Laboratory, Technical
Report. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 3035,1960
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1900 ppb/6H/31D-I
TOXIC EFFECTS :
Blood - changes in bone marrow (not otherwise specified)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
REFERENCE :
CRDLR* U.S. Army Chemical Research & Development Laboratory, Technical
Report. (Edgewood Arsenal, MD 21010) Volume(issue)/page/year: 3035,1960
*** END OF RECORD ***