*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MI7630000
CHEMICAL NAME           : 4-Heptanamine, 4-propyl-
CAS REGISTRY NUMBER     : 61822-36-4
BEILSTEIN REFERENCE NO. : 1735003
REFERENCE               : 3-04-00-00402 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C10-H23-N
MOLECULAR WEIGHT        : 157.34
WISWESSER LINE NOTATION : ZX3&3&3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Diprobutina
   * Diprobutine
   * 1,1-Dipropylbutylamine
   * LCG-21519
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 9,121,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 23 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 9,121,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   3,454,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 9,121,1978
 
                            *** END OF RECORD ***