*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : MJ1500000 CHEMICAL NAME : Heptanethiol, methyl- CAS REGISTRY NUMBER : 63834-87-7 LAST UPDATED : 199012 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C8-H18-S MOLECULAR WEIGHT : 146.32 WISWESSER LINE NOTATION : SH7 &261 COMPOUND DESCRIPTOR : Primary Irritant SYNONYMS/TRADE NAMES : * Methyl heptanethiol * tert-Octyl mercaptan *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 85 mg REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 83500 ug/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 51 ppm/4H TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement Lungs, Thorax, or Respiration - cyanosis REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1594 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 12900 ug/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 47 ppm/4H TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory stimulation Behavioral - convulsions or effect on seizure threshold REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 19,171,1958 *** END OF RECORD ***