*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MJ1970000
CHEMICAL NAME           : Heptanoic acid,
                          7-((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)ami
                          no)-
CAS REGISTRY NUMBER     : 57574-09-1
BEILSTEIN REFERENCE NO. : 2170218
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H27-N-O2
MOLECULAR WEIGHT        : 337.50
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Amineptine
   * 7-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)amino)heptanoic acid
   * Survector
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 84 mg/kg/2W-I
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
   Liver - liver function tests impaired
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   GUTTAK Gut.  (British Medical Journal, Box 560B, Kennebunkport, ME 04046)
   V.1-    1960-  Volume(issue)/page/year: 27,726,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 17,37,1986
 
                            *** END OF RECORD ***