*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MJ3240000
CHEMICAL NAME           : 2-Heptanol, 6-amino-2-methyl-, hydrochloride
CAS REGISTRY NUMBER     : 543-15-7
OTHER CAS REGISTRY NOS. : 53572-44-4
LAST UPDATED            : 199012
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H19-N-O.Cl-H
MOLECULAR WEIGHT        : 181.74
WISWESSER LINE NOTATION : ZY1&3XQ1&1
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * 6-Amino-2-methyl-2-heptanol hydrochloride
   * Cardiosintol
   * Cortensor
   * EA-85
   * Heptaminol hydrochloride
   * Heptamyl hydrochloride
   * 2-Heptylamine, 6-hydroxy-6-methyl-, hydrochloride
   * 2-Methyl-6-amino-2-heptanol hydrochloride
   * 6-Methyl-2-amino-6-heptanol hydrochloride
   * R.P. 2831
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 28 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Kidney, Ureter, Bladder - urine volume increased
   Skin and Appendages - sweating
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 103,178,1951
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 103,178,1951
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 670 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 20,515,1970
 
                            *** END OF RECORD ***