*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MJ9652150
CHEMICAL NAME           : 5-Heptenoic acid,
                          7-(2-((3-(3-chlorophenoxy)-2-hydroxypropyl)thio)-3,5-
                          dihydroxycyclopentyl)-
CAS REGISTRY NUMBER     : 61507-56-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H29-Cl-O6-S
MOLECULAR WEIGHT        : 445.01
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   *   7-(2-((3-(3-Chlorophenoxy)-2-hydroxypropyl)thio)-3,5-dihydroxycyclopenty
     l)-5-heptenoic acid
   * EMD-34946
   * Luprostiol
   * Pronilin
   * Prosolvin
   * Prostianol
   * Reprodin
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 25 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Fertility - abortion
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 35,62A,1987
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 25 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 35,62A,1987
 
                            *** END OF RECORD ***