*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MK6251100
CHEMICAL NAME           : Herpestis monniera Linn., alkaloidal fraction
SUBSTANCE DEFINITION :
   Plant belonging to the family Scrophularineae
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 5,136,1961
LAST UPDATED            : 199506
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 85 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - ganglion blocker
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   IJPPAZ Indian Journal of Physiology and Pharmacology.  (All India Institute
   of Medical Sciences, Dept. of Physiology, Ansari Nagar, New Delhi 110 029,
   India)  V.1-    1957-  Volume(issue)/page/year: 5,136,1961
 
                            *** END OF RECORD ***