*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MP9100000
CHEMICAL NAME           : 4-Hexenylamine, N,1,5-trimethyl-
CAS REGISTRY NUMBER     : 503-01-5
BEILSTEIN REFERENCE NO. : 1742093
REFERENCE               : 3-04-00-00467 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C9-H19-N
MOLECULAR WEIGHT        : 141.29
WISWESSER LINE NOTATION : 1Y1&U3Y1&M1
SYNONYMS/TRADE NAMES :
   * Isometheptene
   * Isonyl
   * 6-Methylamino-2-methylheptene
   * Methylisooctenylamine
   * 2-Methyl-6-methylamino-2-heptene
   * Methyloctenylamine
   * Octanil
   * Octin
   * Octinum
   * Octon
   * N,1,5-Trimethyl-4-hexenylamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 134 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 116,377,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 116,377,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FDMU** "Zur Pharmakologie des Octins, Dissertation," Fiegenbaum, A.,
   Pharmakologischen Institut der Westfalischen Wilhelms-Universitat, Munster,
   Fed. Rep. Ger., 1935  Volume(issue)/page/year: -,-,1935
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 227,71,1955
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FDMU** "Zur Pharmakologie des Octins, Dissertation," Fiegenbaum, A.,
   Pharmakologischen Institut der Westfalischen Wilhelms-Universitat, Munster,
   Fed. Rep. Ger., 1935  Volume(issue)/page/year: -,-,1935

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***