*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MT9192200
CHEMICAL NAME           : Hydantoin,
                          5,5-bis(p-methoxyphenyl)-3-(2-piperidinoethyl)-,
                          hemisulfate
CAS REGISTRY NUMBER     : 101564-64-1
LAST UPDATED            : 199112
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H29-N3-O4.1/2H2-O4-S
MOLECULAR WEIGHT        : 472.56
WISWESSER LINE NOTATION : T6NTJ A2- CT5MVNV EHJ ER DO1& ER DO1 2 &..H2.S-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5,5-Bis(p-methoxyphenyl)-3-(2-piperidinoethyl)hydantoin hemisulfate
   * 3-beta-(1-Piperidino)etil-5,5-bis-(p-metossifenil)idantoina solfato
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,809,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,809,1960
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 33500 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,809,1960
 
                            *** END OF RECORD ***