*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MT9193000
CHEMICAL NAME           : Hydantoin,
                          5,5-bis(alpha,alpha,alpha-trifluoro-p-tolyl)-
CAS REGISTRY NUMBER     : 62031-95-2
BEILSTEIN REFERENCE NO. : 0767998
REFERENCE               : 5-24-08-00427 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H10-F6-N2-O2
MOLECULAR WEIGHT        : 388.29
WISWESSER LINE NOTATION : T5MVMV EHJ ER DXFFF& ER DXFFF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5,5-Bis(4-(trifluoromethyl)phenyl)hydantoin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,843,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,843,1981
 
                            *** END OF RECORD ***