*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MU1350000
CHEMICAL NAME           : Hydantoin,
                          5,5-diphenyl-3-(3-(2-methylpiperidino)propyl)-2-thio-
                          , monohydrochloride
CAS REGISTRY NUMBER     : 101564-67-4
LAST UPDATED            : 199112
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H29-N3-O-S.Cl-H
MOLECULAR WEIGHT        : 444.08
WISWESSER LINE NOTATION : T6NTJ B1 A3- CT5MYNV EHJ BUS ER& ER &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5,5-Diphenyl-3-(3-(2-methylpiperidino)propyl)-2-thio-hydantoin  
   hydrochloride
   * 3-gamma-(alpha-Metil-1-piperidino)propil-5,5-difeniltioidantoina  
   cloridrato
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,809,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,809,1960
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3630 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,809,1960
 
                            *** END OF RECORD ***