*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : MU7395000
CHEMICAL NAME : Hydrazine, 1-acetyl-2-(4-hydroxymethylphenyl)-
CAS REGISTRY NUMBER : 65734-38-5
LAST UPDATED : 198910
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C9-H12-N2-O2
MOLECULAR WEIGHT : 180.23
WISWESSER LINE NOTATION : Q1R DMMV1
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* N-Acetyl-N'-(p-hydroxymethyl)phenylhydrazine
* N'-Acetyl-4-(hydroxymethyl)phenylhydrazine
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 74 gm/kg/85W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria
Vascular - tumors
Lungs, Thorax, or Respiration - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
38,177,1978
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13 gm/kg/26W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 8,1,1981
** MUTATION DATA **
TYPE OF TEST : DNA repair
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 10 umol/L
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
Volume(issue)/page/year: 79,204,1988
TYPE OF TEST : DNA repair
TEST SYSTEM : Rodent - mouse Liver
DOSE/DURATION : 100 umol/L
REFERENCE :
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
Volume(issue)/page/year: 79,204,1988
*** END OF RECORD ***