*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MV0905000
CHEMICAL NAME           : Hydrazine, 1-butyl-2-methyl-, dihydrochloride
CAS REGISTRY NUMBER     : 73454-79-2
LAST UPDATED            : 199109
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H14-N2.2Cl-H
MOLECULAR WEIGHT        : 175.13
WISWESSER LINE NOTATION : 3MM1 &GH 2
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1-Butyl-2-methyl-hydrazine dihydrochloride
   * 1-Methyl-2-butyl-hydrazine dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   23HZAR "Carcinoma of the Colon and Antecedent Epithelium," Burdette, W.J.,
   ed., Springfield, IL C.C. Thomas, 1970  Volume(issue)/page/year: -,267,1970
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1425 mg/kg/57W-T
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Gastrointestinal - tumors
REFERENCE :
   23HZAR "Carcinoma of the Colon and Antecedent Epithelium," Burdette, W.J.,
   ed., Springfield, IL C.C. Thomas, 1970  Volume(issue)/page/year: -,267,1970
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1275 mg/kg/51W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Gastrointestinal - tumors
REFERENCE :
   23HZAR "Carcinoma of the Colon and Antecedent Epithelium," Burdette, W.J.,
   ed., Springfield, IL C.C. Thomas, 1970  Volume(issue)/page/year: -,267,1970
 
                            *** END OF RECORD ***