*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MW4895000
CHEMICAL NAME           : Hydrocinnamaldehyde, p-tert-butyl-alpha-methyl-
CAS REGISTRY NUMBER     : 80-54-6
BEILSTEIN REFERENCE NO. : 0880140
REFERENCE               : 4-07-00-00802 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C14-H20-O
MOLECULAR WEIGHT        : 204.34
WISWESSER LINE NOTATION : VHY1&1R DX1&1&1
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Benzenepropanal, 4-(1,1-dimethylethyl)-alpha-methyl-
   * p-tert-Butyl-alpha-methylhydrocinnamaldehyde
   * p-tert-Butyl-alpha-methylhydrocinnamic aldehyde
   * Lilial
   * Lilyal
   * alpha-Methyl-p-(tert-butyl)hydrocinnamaldehyde
   * alpha-Methyl, beta-(p-tert-butylphenyl)propionaldehyde
   * Propionaldehyde, beta-(4-tert-butylphenyl)-alpha-methyl-
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Moderate
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 16,659,1978
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 16,659,1978
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0524035-3
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 gm/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0524035-3

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83218
       No. of Facilities: 21 (estimated)
       No. of Industries: 1
       No. of Occupations: 19
       No. of Employees: 2073 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83218
       No. of Facilities: 2349 (estimated)
       No. of Industries: 13
       No. of Occupations: 26
       No. of Employees: 34278 (estimated)
       No. of Female Employees: 20486 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***