*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MW4900000
CHEMICAL NAME           : Hydrocinnamaldehyde, p-isopropyl-alpha-methyl-
CAS REGISTRY NUMBER     : 103-95-7
BEILSTEIN REFERENCE NO. : 2047689
REFERENCE               : 4-07-00-00788 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C13-H18-O
MOLECULAR WEIGHT        : 190.31
WISWESSER LINE NOTATION : VHY1&1R DY1&1
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Aldehyde B
   * Benzenepropanal, alpha-methyl-4-(1-methylethyl)-
   * Cyclamal
   * Cyclamen aldehyde
   * p-Isopropyl-alpha-methylhydrocinnamaldehyde
   * p-Isopropyl-alpha-methylhydrocinnamic aldehyde
   * p-Isopropyl-alpha-methylphenylpropyl aldehyde
   * alpha-Methyl-p-isopropylhydrocinnamaldehyde
   * 2-Methyl-3-(p-isopropylphenyl)propionaldehyde
   * alpha-Methyl-4-(1-methylethyl)benzenepropanal
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Human
DOSE/DURATION           : 15 mg/48H
REACTION SEVERITY       : Mild
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 12,397,1974
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg
REACTION SEVERITY       : Mild
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535055
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3810 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - coma
   Skin and Appendages - hair
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 2,327,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - somnolence (general depressed activity)
   Skin and Appendages - hair
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535055

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - T1531
       No. of Facilities: 15 (estimated)
       No. of Industries: 1
       No. of Occupations: 16
       No. of Employees: 2279 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T1531
       No. of Facilities: 5372 (estimated)
       No. of Industries: 15
       No. of Occupations: 25
       No. of Employees: 61118 (estimated)
       No. of Female Employees: 31031 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***