*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MW5095000
CHEMICAL NAME           : Hydrocinnamic acid, p-(bis(2-chloroethyl)amino)-
CAS REGISTRY NUMBER     : 6746-11-8
BEILSTEIN REFERENCE NO. : 3059603
REFERENCE               : 4-14-00-01532 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C13-H17-Cl2-N-O2
MOLECULAR WEIGHT        : 290.21
WISWESSER LINE NOTATION : QV2R DN2G2G
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * p-(Bis(2-chloroethyl)amino)hydrocinnamic acid
   * 3-(p-(Bis(2-chloroethyl)amino)phenyl)propionic acid
   * CB 1332
   * p-N,N-Di-(2-chloroethyl)aminophenylpropionic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   5,192,1960
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Unreported
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 160,228,1969

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal

 
                            *** END OF RECORD ***