*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : MW6500000 CHEMICAL NAME : Hydrocupreine, O(sup 6')-isooctyl-, dihydrochloride CAS REGISTRY NUMBER : 605-08-3 LAST UPDATED : 199709 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C27-H40-N2-O2.2Cl-H MOLECULAR WEIGHT : 497.61 SYNONYMS/TRADE NAMES : * (9R)-10,11-Dihydro-6'-((6-methylheptyl)oxy)cinchonan-9-ol dihydrochloride * Hydrocupreine 6-methylheptyl ether dihydrochloride * Isooctylhydrocupreine dihydrochloride * sec-Octylhydrocupreine dihydrochloride * Vuzin dihydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes REFERENCE : ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin. (Berlin, Fed. Rep. Ger.) V.1-139, 1913-65. For publisher information, see REXMAS. Volume(issue)/page/year: 11,257,1920 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Cardiac - other changes Lungs, Thorax, or Respiration - other changes REFERENCE : ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin. (Berlin, Fed. Rep. Ger.) V.1-139, 1913-65. For publisher information, see REXMAS. Volume(issue)/page/year: 11,257,1920 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 9600 ug/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema Blood - other changes REFERENCE : ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin. (Berlin, Fed. Rep. Ger.) V.1-139, 1913-65. For publisher information, see REXMAS. Volume(issue)/page/year: 11,257,1920 *** END OF RECORD ***