*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : MX3016000 CHEMICAL NAME : Hydroquinidine CAS REGISTRY NUMBER : 1435-55-8 LAST UPDATED : 199607 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H26-N2-O2 MOLECULAR WEIGHT : 326.48 COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)- * (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol * Dihydroquinidine * 10,11-Dihydroquinidine * Hydroconquinine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 12 mg/kg TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - headache Cardiac - EKG changes not diagnostic of specified effects REFERENCE : CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 18,659,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56500 ug/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,184,1945 *** END OF RECORD ***