*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NC3800000
CHEMICAL NAME           : Hydroxylamine, N-methyl-
CAS REGISTRY NUMBER     : 593-77-1
BEILSTEIN REFERENCE NO. : 1730792
REFERENCE               : 4-04-00-03299 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C-H5-N-O
MOLECULAR WEIGHT        : 47.07
WISWESSER LINE NOTATION : QM1
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * N-Hydroxymethylamine
   * Methanamine, N-hydroxy-
   * Methylhydroxylamine
   * beta-Methylhydroxylamine
   * NCI-C60066
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 188 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,288,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 1 mol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 4,517,1967
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 4,517,1967
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 50 umol/L
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   32,667,1964
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Cells - not otherwise specified
DOSE/DURATION           : 50 umol/L
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   32,667,1964

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: N crassa-reversion

 
                            *** END OF RECORD ***