*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NH6737000
CHEMICAL NAME           : Ibogamine-18-carboxylic acid,
                          20-hydroxy-12-methoxy-13-((3-alpha)-17-methoxy-17-oxo
                          vobasan- 3-yl)-, methyl ester, (20S)-
CAS REGISTRY NUMBER     : 5130-80-3
LAST UPDATED            : 198311
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C43-H52-N4-O6
MOLECULAR WEIGHT        : 720.99
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Voacaline
   * Voacorine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 15,617,1957
 
                            *** END OF RECORD ***