*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NH7550000
CHEMICAL NAME           : Ichthammol
CAS REGISTRY NUMBER     : 8029-68-3
OTHER CAS REGISTRY NOS. : 1394-96-3
LAST UPDATED            : 199701
DATA ITEMS CITED        : 8
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Ammonium bithiolicum
   * Ammoniumbituminosulfonate DAB
   * Ammonium ichthosulfonate
   * Ammonium sulfoichthyolate
   * Amsubit
   * Fungichthol
   * Hirathiol
   * Ichden
   * Ichtammon
   * Ichthadone
   * Ichthalum
   * Ichthammonium
   * Ichthium
   * Ichthosan
   * Ichthosauran
   * Ichthosulfol
   * Ichthymall
   * Ichthynat
   * Ichthyol
   * Ichthyopon
   * Ichthysalle
   * Leukichthol
   * Lithol
   * Perichthol
   * Petrosulpho
   * Piscarol
   * Pisciol
   * Saurol
   * Subitol
   * Sulfogenol
   * Thilaven
   * Thiolin
   * Thiozin
   * Trasulphane
   * Tumenol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Gastrointestinal - nausea or vomiting
REFERENCE :
   AMLTAS Annales de Medecine Legale et de Criminologie.  (Paris, France)
   V.31-38, 1951-58.  For publisher information, see MLDCAS.
   Volume(issue)/page/year: 37,248,1957
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,844,1994
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >21500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 44,844,1994
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 6,199,1956
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 6,199,1956

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83294
       No. of Facilities: 263 (estimated)
       No. of Industries: 10
       No. of Occupations: 4
       No. of Employees: 907 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83294
       No. of Facilities: 48 (estimated)
       No. of Industries: 2
       No. of Occupations: 1
       No. of Employees: 79 (estimated)
       No. of Female Employees: 17 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***