*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : MV5900000
CHEMICAL NAME : Hydrazine, (alpha-methylbenzyl)-, oxalate
CAS REGISTRY NUMBER : 2126-84-3
LAST UPDATED : 199410
DATA ITEMS CITED : 9
MOLECULAR FORMULA : C8-H12-N2.C2-H2-O4
MOLECULAR WEIGHT : 226.26
WISWESSER LINE NOTATION : ZMY1&R &QVVQ
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Mebanazine oxalate
* alpha-Phenylethylhydrazine oxalate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 458 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8,
1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year:
5,125,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 254 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8,
1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year:
5,125,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 138 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
41,1469,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 121 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8,
1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year:
5,125,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 85 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8,
1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year:
5,125,1966
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 4400 nmol/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
41,1469,1981
TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 2200 nmol/plate
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 9,287,1982
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 10 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 5,343,1968
TYPE OF TEST : DNA damage
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - mouse
DOSE/DURATION : 750 mg/kg/5D (Continuous)
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 9,287,1982
*** END OF RECORD ***