*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI3019500
CHEMICAL NAME           : Imidazo(2,1-a)isoquinoline,
                          2,3-dihydro-5-(4-(1-piperidinylmethyl)phenyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 115621-95-9
LAST UPDATED            : 199603
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C23-H25-N3.2Cl-H
MOLECULAR WEIGHT        : 416.43
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,3-Dihydro-5-(4-(1-piperidinylmethyl)phenyl)imidazo(2,1-a)isoquinoline  
   dihydrochloride
   *   5-(4'-Piperidinomethylphenyl)-2,3-dihydroimidazo(2,1-a)isochinolin-dihyd
     rochlorid
   * SDZ 62-434
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 45,1133,1995
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 45,1133,1995
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 45,1133,1995
 
                            *** END OF RECORD ***