*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI4805000
CHEMICAL NAME           : 1H-Imidazole,
                          4,5-dihydro-2-((2-methylbenzo(b)thien-3-yl)methyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 5090-37-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C13-H14-N2-S.Cl-H
MOLECULAR WEIGHT        : 266.81
WISWESSER LINE NOTATION : T56 BSJ C1 D1- BT5M CN BUTJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,5-Dihydro-2-((2-methylbenzo(b)thien-3-yl)methyl)-1H-imidazole  
   hydrochloride
   * Ellsyl
   * Elsyl
   * EX 10-781
   * H 1032
   * 2-((2-Methylbenzo(b)thien-3-yl)methyl)-2-imidazoline hydrochloride
   * 2-Methyl-3-(delta(sup 2)-imidazolinylmethyl)benzo(b)thiophene  
   hydrochloride
   * alpha-Metil-beta-(2-metilene-4,5-diidroimidazolil)benzotiofane cloridrato
   * Metizoline hydrochloride
   * RMI 10,482A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 74 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 21,204,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 155 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 21,204,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 49 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 21,204,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy)
   V.8-43    1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 21,204,1966
 
                            *** END OF RECORD ***