*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI6450000
CHEMICAL NAME           : 1H-Imidazole, 2-isopropyl-1-methyl-5-nitro-
CAS REGISTRY NUMBER     : 14885-29-1
BEILSTEIN REFERENCE NO. : 0744577
REFERENCE               : 5-23-05-00207 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C7-H11-N3-O2
MOLECULAR WEIGHT        : 169.21
WISWESSER LINE NOTATION : T5N CNJ A1 BY1&1 ENW
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Ipronidazole
   * Ipropran
   * 2-Isopropyl-1-methyl-5-nitroimidazole
   * 1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole
   * Ro 7-1554
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - turkey
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   POSCAL Poultry Science.  (Poultry Science Assoc., Inc., 309 W. Clark St.,
   Champaign, IL 61820) V.1-    1921-  Volume(issue)/page/year: 49,92,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 18 umol/L
REFERENCE :
   TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis.  (Alan R. Liss, Inc.,
   41 E. 11th St., New York, NY 10003)  V.1-    1980- Volume(issue)/page/year:
   3,51,1983
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,155,1977
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Klebsiella pneumoniae
DOSE/DURATION           : 50 umol/L/20H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 66,207,1979
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 50 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,155,1977
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 5 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 86,243,1981
 
                            *** END OF RECORD ***