*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI8505800
CHEMICAL NAME           : Imidazole-4-thiocarboxamide,
                          5-amino-1-(beta-D-ribofuranosyl)-
CAS REGISTRY NUMBER     : 19508-94-2
BEILSTEIN REFERENCE NO. : 0894547
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H14-N4-O4-S
MOLECULAR WEIGHT        : 274.33
WISWESSER LINE NOTATION : T5OTJ B1Q CQ DQ E- AT5N CNJ DYZUS EZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Amino-1-(beta-D-ribofuranosyl)imidazole-4-thiocarboxamide
   * 1-(beta-D-Ribofuranosyl)-5-amino-4-imidazolethiocarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 780 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 16,2080,1968
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3300 mg/kg/5D-I
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 16,2080,1968
 
                            *** END OF RECORD ***