*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI8925000
CHEMICAL NAME           : 1-Imidazolidinecarboxylic acid,
                          2,5-dioxo-4,4-diphenyl-, ethyl ester
CAS REGISTRY NUMBER     : 1097-57-0
BEILSTEIN REFERENCE NO. : 0762005
REFERENCE               : 5-24-08-00381 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C18-H16-N2-O4
MOLECULAR WEIGHT        : 324.36
WISWESSER LINE NOTATION : T5MVNV EHJ CVO2 ER& ER
SYNONYMS/TRADE NAMES :
   * 3-Ethoxycarbonyl-5,5-diphenyl hydantoin
   * P 6127
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3500 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Blood - changes in cell count (unspecified)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 156,261,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Blood - changes in cell count (unspecified)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 156,261,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 395 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Blood - changes in cell count (unspecified)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 156,261,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 355 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Blood - changes in cell count (unspecified)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 156,261,1965
 
                            *** END OF RECORD ***